Endocrine Abstracts

In women, gonadotropin releasing hormone (GnRH) is secreted from the hypothalamus and conveyed via the portal vasculature to the anterior pituitary gland every 60-90 minutes. This binds GnRH receptor and triggers pulsatile release of gonadotrophin hormones, Follicle stimulating and Luteinising hormone (FSH and LH), which stimulate and regulate folliculogenesis. The interdependence of these events accounts for the high number of cycling disorders in women, and the origin of the...